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Application of arterial spin labeling perfusion MRI to differentiate benign from malignant intracranial meningiomas. Improved Spatiotemporal Resolution of Dynamic Susceptibility Contrast Perfusion MRI in Brain Tumors Using Simultaneous Multi-Slice Echo-Planar Imaging. Evidence and Context of Use for Contrast Enhancement as a Surrogate of Disease Burden and Treatment Response in Malignant Glioma. Radiologic progression of glioblastoma under therapy – an exploratory analysis of AVAglio. Detection of immune responses after immunotherapy in glioblastoma using PET and MRI. Diffusion MRI Phenotypes Predict Overall Survival Benefit from Anti-VEGF Monotherapy in Recurrent Glioblastoma: Converging Evidence from Phase II Trials. Perfusion and diffusion MRI signatures in histologic and genetic subtypes of WHO grade II-III diffuse gliomas. Metabolic Imaging Using Proton Magnetic Spectroscopy as a Predictor of Outcome After Surgery for Cervical Spondylotic Myelopathy. Pseudoprogression, radionecrosis, inflammation or true tumor progression? challenges associated with glioblastoma response assessment in an evolving therapeutic landscape. Modified Criteria for Radiographic Response Assessment in Glioblastoma Clinical Trials. Evaluation of Encephaloduroarteriosynangiosis Efficacy Using Probabilistic Independent Component Analysis Applied to Dynamic Susceptibility Contrast Perfusion MRI. Effects of MRI Protocol Parameters, Preload Injection Dose, Fractionation Strategies, and Leakage Correction Algorithms on the Fidelity of Dynamic-Susceptibility Contrast MRI Estimates of Relative Cerebral Blood Volume in Gliomas. Brain white matter changes associated with urological chronic pelvic pain syndrome: multisite neuroimaging from a MAPP case-control study.
Simulation, phantom validation, and clinical evaluation of fast pH-weighted molecular imaging using amine chemical exchange saturation transfer echo planar imaging (CEST-EPI) in glioma at 3 T. Symptom Variability and Early Symptom Regression in the MAPP Study: A Prospective Study of Urological Chronic Pelvic Pain Syndrome. Dynamic Susceptibility Contrast MR Imaging in Glioma: Review of Current Clinical Practice. Baseline pretreatment contrast enhancing tumor volume including central necrosis is a prognostic factor in recurrent glioblastoma: evidence from single and multicenter trials. Human TERT promoter mutation enables survival advantage from MGMT promoter methylation in IDH1 wild-type primary glioblastoma treated by standard chemoradiotherapy. Multisite, multimodal neuroimaging of chronic urological pelvic pain: Methodology of the MAPP Research Network. Modeling the efficacy of the extent of surgical resection in the setting of radiation therapy for glioblastoma. Traumatic hemorrhagic brain injury: impact of location and resorption on cognitive outcome. ACRIN 6684: Assessment of Tumor Hypoxia in Newly Diagnosed Glioblastoma Using 18F-FMISO PET and MRI. Response Assessment in Neuro-Oncology working group and European Association for Neuro-Oncology recommendations for the clinical use of PET imaging in gliomas. Improved Leakage Correction for Single-Echo Dynamic Susceptibility Contrast Perfusion MRI Estimates of Relative Cerebral Blood Volume in High-Grade Gliomas by Accounting for Bidirectional Contrast Agent Exchange. Contrast-enhancing tumor growth dynamics of preoperative, treatment-naive human glioblastoma. Bidirectional Contrast agent leakage correction of dynamic susceptibility contrast (DSC)-MRI improves cerebral blood volume estimation and survival prediction in recurrent glioblastoma treated with bevacizumab. Assessing Variability in Brain Tumor Segmentation to Improve Volumetric Accuracy and Characterization of Change. The Impact of T2/FLAIR Evaluation per RANO Criteria on Response Assessment of Recurrent Glioblastoma Patients Treated with Bevacizumab. Topographical Distribution of Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex. Pain and Interoception Imaging Network (PAIN): A multimodal, multisite, brain-imaging repository for chronic somatic and visceral pain disorders.
Diffusion MR Characteristics Following Concurrent Radiochemotherapy Predicts Progression-Free and Overall Survival in Newly Diagnosed Glioblastoma. Association between lesion location and language function in adult glioma using voxel-based lesion-symptom mapping. Prefrontal and Hippocampal Brain Volume Deficits: Role of Low Physical Activity on Brain Plasticity in First-Episode Schizophrenia Patients. DTI of tuber and perituberal tissue can predict epileptogenicity in tuberous sclerosis complex. Immunotherapy response assessment in neuro-oncology: a report of the RANO working group. Unique Microstructural Changes in the Brain Associated with Urological Chronic Pelvic Pain Syndrome (UCPPS) Revealed by Diffusion Tensor MRI, Super-Resolution Track Density Imaging, and Statistical Parameter Mapping: A MAPP Network Neuroimaging Study. Prediction of Neurological Impairment in Cervical Spondylotic Myelopathy using a Combination of Diffusion MRI and Proton MR Spectroscopy. Impact of Software Modeling on the Accuracy of Perfusion MRI in Glioma. Standardized Brain Tumor Imaging Protocol for Clinical Trials. Ionic charge transport between blockages: Sodium cation conduction in freshly excised bulk brain tissue. Parametric Response Mapping of Apparent Diffusion Coefficient as an Imaging Biomarker to Distinguish Pseudoprogression from True Tumor Progression in Peptide-Based Vaccine Therapy for Pediatric Diffuse Intrinsic Pontine Glioma. Consensus recommendations for a standardized Brain Tumor Imaging Protocol in clinical trials. The Risk of Acute Spinal Cord Injury After Minor Trauma in Patients With Preexisting Cervical Stenosis. pH-weighted molecular imaging of gliomas using amine chemical exchange saturation transfer MRI. Radial expansion rates and tumor growth kinetics predict malignant transformation in contrast-enhancing low-grade diffuse astrocytoma. Novel Magnetic Resonance Imaging Techniques in Brain Tumors. Response Assessment and Magnetic Resonance Imaging Issues for Clinical Trials Involving High-Grade Gliomas. Quantitative multiparametric MRI in uveal melanoma: increased tumor permeability may predict monosomy 3. Patient-specific characterization of the invasiveness and proliferation of low-grade gliomas using serial MR imaging and a mathematical model of tumor growth. Quantification of Nonenhancing Tumor Burden in Gliomas Using Effective T2 Maps Derived from Dual-Echo Turbo Spin-Echo MRI. MRI perfusion measurements calculated using advanced deconvolution techniques predict survival in recurrent glioblastoma treated with bevacizumab. Correlation between degree of subvoxel spinal cord compression measured with super-resolution tract density imaging and neurological impairment in cervical spondylotic myelopathy. Patterns of brain structural connectivity differentiate normal weight from overweight subjects. Brain White Matter Abnormalities in Female Interstitial Cystitis/Bladder Pain Syndrome: A MAPP Network Neuroimaging Study. Diffusion MRI quality control and functional diffusion map results in ACRIN 6677/RTOG 0625: a multicenter, randomized, phase II trial of bevacizumab and chemotherapy in recurrent glioblastoma. Arterial spin-labeling perfusion MRI stratifies progression-free survival and correlates with epidermal growth factor receptor status in glioblastoma. Relationship Between [18F]FDOPA PET Uptake, Apparent Diffusion Coefficient (ADC), and Proliferation Rate in Recurrent Malignant Gliomas. Relationship between chronic nonurological associated somatic syndromes and symptom severity in urological chronic pelvic pain syndromes: baseline evaluation of the MAPP study. Longitudinal DSC-MRI for Distinguishing Tumor Recurrence From Pseudoprogression in Patients With a High-grade Glioma. Radiogenomics and imaging phenotypes in glioblastoma: novel observations and correlation with molecular characteristics. A novel bicompartmental mathematical model of glioblastoma multiforme. Nitroxoline induces apoptosis and slows glioma growth in vivo. Advances in MR imaging for cervical spondylotic myelopathy.
Hypervascular tumor volume estimated by comparison to a large-scale cerebral blood volume radiographic atlas predicts survival in recurrent glioblastoma treated with bevacizumab. Report of the Jumpstarting Brain Tumor Drug Development Coalition and FDA clinical trials neuroimaging endpoint workshop (January 30, 2014, Bethesda MD). Impact of imaging measurements on response assessment in glioblastoma clinical trials. Pros and cons of current brain tumor imaging. Emerging techniques and technologies in brain tumor imaging. The MAPP research network: design, patient characterization and operations. The MAPP research network: a novel study of urologic chronic pelvic pain syndromes. Treatment response evaluation using 18F-FDOPA PET in patients with recurrent malignant glioma on bevacizumab therapy. Efficient calculation of SAMPL4 hydration free energies using OMEGA, SZYBKI, QUACPAC, and Zap TK. Deferred use of bevacizumab for recurrent glioblastoma is not associated with diminished efficacy. Diffusion tensor imaging predicts functional impairment in mild-to-moderate cervical spondylotic myelopathy. Combined low-dose contrast-enhanced MR angiography and perfusion for acute ischemic stroke at 3T: A more efficient stroke protocol. Recurrent glioblastoma treated with bevacizumab: contrast-enhanced T1-weighted subtraction maps improve tumor delineation and aid prediction of survival in a multicenter clinical trial. Short-interval estimation of proliferation rate using serial diffusion MRI predicts progression-free survival in newly diagnosed glioblastoma treated with radiochemotherapy. Nonlinear distortion correction of diffusion MR images improves quantitative DTI measurements in glioblastoma. Increased sensitivity to radiochemotherapy in IDH1 mutant glioblastoma as demonstrated by serial quantitative MR volumetry. Glioblastoma treatment using perphenazine to block the subventricular zone’s tumor trophic functions. Altered functional connectivity of the default mode network in diffuse gliomas measured with pseudo-resting state fMRI. Pretreatment ADC histogram analysis is a predictive imaging biomarker for bevacizumab treatment but not chemotherapy in recurrent glioblastoma. Imaging techniques in spinal cord injury. Regional and voxel-wise comparisons of blood flow measurements between dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) and arterial spin labeling (ASL) in brain tumors.
Imaging biomarkers for antiangiogenic therapy in malignant gliomas. Peripheral vascular disease as remote ischemic preconditioning, for acute stroke. Metabolomic analysis of cerebral spinal fluid from patients with severe brain injury. Diffusion tensor imaging detects microstructural reorganization in the brain associated with chronic irritable bowel syndrome. Perfusion deficits detected by arterial spin-labeling in patients with TIA with negative diffusion and vascular imaging. Proton magnetic resonance spectroscopy of human cervical spondylosis at 3T. PET Parametric Response Mapping for Clinical Monitoring and Treatment Response Evaluation in Brain Tumors. Magnetic Resonance Imaging of Glioma in the Era of Antiangiogenic Therapy. Dyspepsia: Structural changes in functional gastrointestinal disorders. Identifying the mesenchymal molecular subtype of glioblastoma using quantitative volumetric analysis of anatomic magnetic resonance images. Periprocedural arterial spin labeling and dynamic susceptibility contrast perfusion in detection of cerebral blood flow in patients with acute ischemic syndrome. Pre- and post-contrast three-dimensional double inversion-recovery MRI in human glioblastoma. Combined analysis of O6-methylguanine-DNA methyltransferase protein expression and promoter methylation provides optimized prognostication of glioblastoma outcome. Quantitative probabilistic functional diffusion mapping in newly diagnosed glioblastoma treated with radiochemotherapy. Detection of 2-hydroxyglutaric acid in vivo by proton magnetic resonance spectroscopy in U87 glioma cells overexpressing isocitrate dehydrogenase-1 mutation. Probabilistic radiographic atlas of glioblastoma phenotypes. Fine-tuning robot-assisted radical prostatectomy planning with MRI.
Diffusion tensor magnetic resonance tractography of the prostate: feasibility for mapping periprostatic fibers. 18F-FDOPA and 18F-FLT positron emission tomography parametric response maps predict response in recurrent malignant gliomas treated with bevacizumab. Persistent diffusion-restricted lesions in bevacizumab-treated malignant gliomas are associated with improved survival compared with matched controls. Apparent diffusion coefficient histogram analysis stratifies progression-free and overall survival in patients with recurrent GBM treated with bevacizumab: a multi-center study. Relationship between tumor enhancement, edema, IDH1 mutational status, MGMT promoter methylation, and survival in glioblastoma. Comparison between intensity normalization techniques for dynamic susceptibility contrast (DSC)-MRI estimates of cerebral blood volume (CBV) in human gliomas. Functional diffusion maps (fDMs) evaluated before and after radiochemotherapy predict progression-free and overall survival in newly diagnosed glioblastoma. Differential gene expression in glioblastoma defined by ADC histogram analysis: relationship to extracellular matrix molecules and survival. 3′-deoxy-3′-18F-fluorothymidine PET and MRI for early survival predictions in patients with recurrent malignant glioma treated with bevacizumab. Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin. Anatomic localization of O6-methylguanine DNA methyltransferase (MGMT) promoter methylated and unmethylated tumors: a radiographic study in 358 de novo human glioblastomas. Quantification of edema reduction using differential quantitative T2 (DQT2) relaxometry mapping in recurrent glioblastoma treated with bevacizumab. Nonlinear registration of diffusion-weighted images improves clinical sensitivity of functional diffusion maps in recurrent glioblastoma treated with bevacizumab.
Novel spinal cord imaging. Graded functional diffusion map-defined characteristics of apparent diffusion coefficients predict overall survival in recurrent glioblastoma treated with bevacizumab. High order diffusion tensor imaging in human glioblastoma. Cell invasion, motility, and proliferation level estimate (CIMPLE) maps derived from serial diffusion MR images in recurrent glioblastoma treated with bevacizumab. Spatially quantifying microscopic tumor invasion and proliferation using a voxel-wise solution to a glioma growth model and serial diffusion MRI. 3D visualization of subdural electrode shift as measured at craniotomy reopening. Quantitative volumetric analysis of conventional MRI response in recurrent glioblastoma treated with bevacizumab. Advances in MRI assessment of gliomas and response to anti-VEGF therapy. Three-dimensional visualization of subdural electrodes for presurgical planning. Volumetric analysis of functional diffusion maps is a predictive imaging biomarker for cytotoxic and anti-angiogenic treatments in malignant gliomas.
High-resolution in vivo diffusion tensor imaging of the injured cat spinal cord using self-navigated, interleaved, variable-density spiral acquisition (SNAILS-DTI). Lesion growth and degeneration patterns measured using diffusion tensor 9.4-T magnetic resonance imaging in rat spinal cord injury. Analysis of SM8 and Zap TK calculations and their geometric sensitivity. Conformer generation with OMEGA: algorithm and validation using high quality structures from the Protein Databank and Cambridge Structural Database. Validation of functional diffusion maps (fDMs) as a biomarker for human glioma cellularity. Utility of functional diffusion maps to monitor a patient diagnosed with gliomatosis cerebri.
Functional correlates of diffusion tensor imaging in spinal cord injury. Characteristics of mid- to long-latency spinal somatosensory evoked potentials following spinal trauma in the rat. Ex vivo diffusion tensor imaging and quantitative tractography of the rat spinal cord during long-term recovery from moderate spinal contusion. Diffusion tensor MR imaging in chronic spinal cord injury. Diffusion tensor MR imaging of the neurologically intact human spinal cord. In vivo diffusion tensor imaging of the rat spinal cord at 9.4T. Morphology and morphometry of human chronic spinal cord injury using diffusion tensor imaging and fuzzy logic. Reactions of hydrogen atom with hydrogen peroxide. Multicoefficient Gaussian-3 calculation of the rate constant for the OH + CH4 reaction and its 12C/13C kinetic isotope effect with emphasis on the effects of coordinate system and torsional treatment. Morphology and morphometry in chronic spinal cord injury assessed using diffusion tensor imaging and fuzzy logic. Explanation of the unusual temperature dependence of the atmospherically important OH + H(2)S –> H(2)O + HS reaction and prediction of the rate constant at combustion temperatures. Gray and white matter delineation in the human spinal cord using diffusion tensor imaging and fuzzy logic. Optimal diffusion tensor indices for imaging the human spinal cord. Statistical thermodynamics of bond torsional modes: tests of separable, almost-separable, and improved Pitzer-Gwinn approximations. A new technique for imaging the human spinal cord in vivo. Interface parameters of impact-induced mild traumatic brain injury. New mechanism for inducing closed head injury in the rat.
